Tegoyes 20mg Capsules

About Tegoyes 20mg Capsules

Tegoyes 20mg Capsules containing the active constituents Tegafur, Gimeracil, and Oteracil are used as anticancer drugs, particularly in the treatment of certain types of cancers such as gastric, colorectal, and other solid tumors.

Inform your doctor if you have blood disorders, kidney issues, viral infections, or dihydropyrimidine dehydrogenase (DPD) deficiency. The Tegoyes 20mg Capsule contains lactose, so mention any sugar intolerance, and use contraception during treatment and for six weeks after.

Brand Name: Tegoyes

Composition: Tegafur, Gimeracil, Oteracil

Mechanism of Action:

Tegafur is metabolized into 5-FU in the body, which inhibits thymidylate synthase, an enzyme essential for DNA synthesis in cancer cells, leading to cell death. Gimeracil enhances the anticancer effects of 5-FU by preventing its rapid degradation, allowing for prolonged exposure of cancer cells to the active drug. Oteracil protects normal tissues, especially the gastrointestinal tract, from the toxic effects of 5-FU, minimizing side effects like severe diarrhea and mucositis.

Uses:

• Gastric Cancer
• Colorectal Cancer

Dosage and Administration:

Administered orally, usually in cycles as per oncologist recommendations, which vary based on cancer type, stage, and patient tolerance.

Side Effect:

• Nausea
• Vomiting
• Loss of appetite
• Diarrhea
• Fatigue
• Stomatitis (mouth sores)
• Hand-foot syndrome
• Cardiotoxicity
• Liver enzyme elevation