Colistin 3 MIU Injection

About Colistin 3 MIU Injection

Colistin 3 MIU Injection contains Colistimethate Sodium, a polymyxin antibiotic used for treating serious infections caused by multidrug-resistant Gram-negative bacteria. When other antibiotics fail, this one is frequently used as a last resort, usually in a hospital setting.

While beginning this medication, let your doctor know if you have any liver or kidney problems, antibiotic sensitivities, or if you are pregnant or nursing. Regular blood tests may be required to check drug levels and kidney function.

Brand Name: Colistin

Composition: Colistimethate Sodium

Mechanism of Action:

Colistin sodium is an inactive prodrug that the body transforms into its active form after administration. Colistin binds to phospholipids and lipopolysaccharides (LPS) found in Gram-negative bacteria's outer membrane to produce a bactericidal effect. Bacterial cell death results from this binding's disruption of the cell membrane, which increases its permeability and allows cellular contents to flow out.

Uses:

Severe Bacterial Infections

Dosage and Administration:

Usually administered as an intravenous infusion. The severity of the infection, the patient's body weight, and renal function all affect dosage. Healthcare practitioners must closely monitor it in order to make adjustments based on toxicity risk and therapeutic response.

Side Effects:

• Dizziness
• Tingling
• Muscle weakness
• Nausea
• Vomiting
• Skin Rash
• Itching
• Diarrhea
• Kidney Damage