I Nem 500 mg Injection

About I Nem 500 mg Injection

I Nem 500mg Injection contains Imipenem and Cilastatin as its active ingredients. It is a combination antibiotic used to treat severe bacterial infections.

If you are pregnant or nursing, let your doctor know about any medications you are taking. Steer clear of alcohol, and if the medication makes you drowsy or dizzy, don't drive.

Brand Name: I Nem

Composition: Imipenem and Cilastatin

Mechanism of Action:

Imipenem inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to cell lysis and death. Whereas Cilastatin Blocks the enzyme dehydropeptidase in the kidneys, which normally deactivates imipenem. This ensures that imipenem reaches the systemic circulation intact and can perform its antibacterial action.

Uses:

• Lower Respiratory Tract Infections: Pneumonia, bronchitis.
• Intra-abdominal Infections: Peritonitis, abdominal abscesses.
• Urinary Tract Infections (UTIs): Complicated UTIs caused by resistant bacteria.
• Gynecological Infections: Endometritis, pelvic inflammatory disease.
• Skin and Soft Tissue Infections: Cellulitis, wound infections.
• Bone and Joint Infections: Osteomyelitis, septic arthritis.
• Septicemia: Blood infections caused by bacteria.

Side Effects:

• Nausea
• Vomiting
• Fever
• Dizziness
• Diarrhea
• Localized pain at the injection site
• Rash
• Swelling
• Seizures