Grastim 300mcg Injection

About Grastim 300mcg Injection

Grastim 300mcg Injection contains Filgrastim that stimulates the bone marrow to produce more white blood cells that help fight infection. Grastim 300 Injection is used to increase the number of white blood cells in patients with HIV infection, severe chronic neutropenia, bone marrow transplantation, and prior to stem cell donation.

Brand Name: Grastim

Composition: Filgrastim

Mechanism of Action:

In order to promote the development, maturation, and discharge of neutrophils into the bloodstream, filgrastim attaches to and activates certain receptors on the surface of neutrophil precursor cells in the bone marrow. This assists in decreasing the likelihood of infections in those with low leukocyte counts.

Uses:

• Neutropenia Due to Chemotherapy
• Bone Marrow or Stem Cell Transplantation
• Severe Chronic Neutropenia
• Hematopoietic Stem Cell Mobilization
• HIV/AIDS-related Neutropenia

Dosage and Administration:

The dosage of Grastim depends on the patients body weight, the condition being treated, and the response to the therapy. It is usually administered as a subcutaneous or intravenous injection.

Side Effects:

• Bone pain
• Injection site reactions (redness, pain, swelling)
• Headache
• Fatigue
• Fever
• Splenic Rupture
• Acute Respiratory Distress Syndrome
• Capillary Leak Syndrome
• Thrombocytopenia (Low Platelet Count)