Palborest 75mg Tablet contains Palbociclib, is used, usually in combination with hormonal anticancer therapy, to treat certain forms of breast cancer (HER2-negative, estrogen receptor-positive) that have metastasized to other organs. For best results, take it with food at the same time every day.
If you are taking medication for an infection, have liver or kidney problems, or have heart disease, let your doctor know before taking Palborest. Since many drugs can interact with this one, please disclose all of the medications you are currently taking.
Brand Name: Palborest
Composition: Palbociclib
Mechanism of Action:
Palbociclib inhibit the CDK4 and CDK6, which are essential for controlling the cell cycle. Palbociclib inhibits the growth of cancer cells by blocking these kinases, which stops cells from moving from the G1 phase of the cell cycle to the S phase.
Uses:
Hormone receptor-positive breast cancer.
Advanced or metastasized breast cancer.
Side effects:
Neutropenia (low white blood cell count)
Fatigue
Nausea
Vomiting
Fever
Diarrhea
Mouth sores
Severe infections due to low neutrophil counts
Liver enzyme elevations
Dosage and Administration:
To improve absorption, Palbociclib should be taken with meals. Instead of chewing or crushing the pills, they should be consumed whole. Palbociclib is normally given orally once day for 21 days at a dose of 75 mg, with a 7-day break (28-day cycle).
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